Evaluation of IL-6 and IgE Levels in Iraqi Patients with Chronic Spontaneous Urticaria (CSU) in Baghdad, Iraq.
نویسندگان
چکیده
A skin condition known as chronic spontaneous urticaria (CSU), which lacks an obvious triggering factor, is characterized by recurrent transient wheals, angioedema, or both for longer than six weeks. the current study was focused to compared and diagnosis CSU using heamatological immunological parameters (White blood cell count, eosinophils (EO), IL-6 Total-IgE, in Chronic Urticaria patients were Clinically diagnosed dermatologists Specialized Center of Allergy Baghdad/Al-Rusafa with age ranged between (11-60), well a control group included 40 (11-60). The results demographic clinical characteristics displayed rate female higher male represented 56.3 43.8% respectively. showed there highly significant differences WBC , Total-IgE ,IL-6 EO but no difference at p ≤ 0.05. percentage high 51-60 21-30 year while those 41-50 had highest, level 211.7 ±38.96 IU/ml, 211.69 ±38.71IU/ml respectively highest 26.4 ±1.77 pg/ml year. count 9.2 ±1.34 cell/cm³blood, 9.3±1.21 cell/cm³blood In same time values various without treatment who undergoes into treatment, Finally ROC discriminated accurate biomarkers CSU.
منابع مشابه
IL-6 Transsignaling in Patients with Chronic Spontaneous Urticaria
BACKGROUND IL-6 trans-signaling is critically involved in the initiation and promotion of inflammatory and autoimmune diseases. Therefore, we investigated the clinical relevance of soluble members of IL-6 trans-signaling system in chronic spontaneous urticaria (CSU). METHODS IL-6, interleukin 6 soluble receptor (IL-6 sR) and soluble gp130 (sgp130) were measured by ELISA method in plasma from ...
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ژورنال
عنوان ژورنال: Ibn Al-Haitham Journal For Pure And Applied Science
سال: 2023
ISSN: ['2521-3407', '1609-4042']
DOI: https://doi.org/10.30526/36.2.3010